The human body is a complex biological system that performs several interconnected processes to maintain life. Among these, circulation, digestion, and respiration play central roles, ensuring that oxygen and nutrients reach every cell and that waste products are removed efficiently. This unit covers the composition and role of blood and lymph, the structure and function of the circulatory system, digestion and absorption of food, as well as the mechanisms of breathing and respiration.

What Are Body Fluids?
Body fluids are the water-based liquids found within the human body. They make up about 60% of a person’s body weight and are crucial for transporting nutrients, removing waste, regulating temperature, and maintaining overall health. They are broadly divided into two main categories:
- Intracellular fluid (ICF): The fluid found inside cells. It makes up about two-thirds of the total body fluid and is rich in potassium, phosphate, and magnesium.
- Extracellular fluid (ECF): The fluid found outside of cells. It makes up about one-third of the total body fluid and is rich in sodium, chloride, and bicarbonate. It includes interstitial fluid (fluid between cells), plasma (the liquid part of blood), and lymph.
The Circulatory System
The circulatory system is a complex network of vessels and organs that circulate blood throughout the body. Its main purpose is to transport essential substances to all cells and remove waste products. It consists of two main parts:
- Cardiovascular System: This includes the heart, blood vessels, and blood.
- Heart: The muscular pump that pushes blood through the body.
- Blood Vessels: The arteries, veins, and capillaries that form the pathways for blood flow.
- Blood: The body’s primary transport medium.
- Lymphatic System: This is a network of vessels that collects excess fluid (lymph) from tissues and returns it to the bloodstream. It also plays a vital role in the immune system.
Components of Blood
Blood is a specialized connective tissue that has two main components:
- Plasma: The liquid matrix of blood, making up about 55% of its volume. It’s a pale yellow fluid that contains water, proteins (like albumin and fibrinogen), electrolytes, hormones, and nutrients.
- Formed Elements: These are the blood cells that are suspended in the plasma, making up about 45% of its volume. They are produced in the bone marrow.
- Red Blood Cells (Erythrocytes): These are biconcave, anucleated cells filled with hemoglobin, a protein that carries oxygen. They are crucial for oxygen transport.
- White Blood Cells (Leukocytes): These are immune cells that defend the body against infection and disease. They are further divided into different types like neutrophils, lymphocytes, and monocytes.
- Platelets (Thrombocytes): Small cell fragments that are essential for blood clotting.

Digestion and Absorption
Digestion and absorption are two interconnected processes that allow the body to break down food and utilize its nutrients. Digestion is the mechanical and chemical process of converting complex food substances into simple, absorbable forms. Absorption is the process by which these simple nutrients are taken up by the body and transported to cells.

The Process of Digestion
Digestion begins in the mouth and involves several organs in the digestive tract.
- Mouth: Food is mechanically broken down by chewing. Saliva, containing the enzyme amylase, begins the chemical digestion of carbohydrates.
- Stomach: Food mixes with gastric juices, including hydrochloric acid and the enzyme pepsin. The acid denatures proteins and kills microbes, while pepsin begins the digestion of proteins. The food is churned into a semi-liquid mixture called chyme.
- Small Intestine: This is the primary site of both digestion and absorption. Chyme from the stomach mixes with digestive juices from the pancreas and bile from the liver.
- Pancreatic enzymes (e.g., amylase, lipase, trypsin) break down carbohydrates, fats, and proteins into their simplest forms.
- Bile, produced by the liver and stored in the gallbladder, emulsifies fats, breaking them into smaller droplets to aid digestion.
The Process of Absorption
Once food is broken down into its simplest components, it is ready for absorption.
- Carbohydrates are broken down into monosaccharides (e.g., glucose).
- Proteins are broken down into amino acids.
- Fats are broken down into fatty acids and glycerol.
Absorption occurs mainly in the small intestine, which has a large surface area due to finger-like projections called villi and microscopic folds called microvilli.
- Amino acids, monosaccharides, water, and water-soluble vitamins are absorbed into the bloodstream through the walls of the small intestine.
- Fatty acids and fat-soluble vitamins are absorbed into the lymphatic system, which eventually drains into the bloodstream.
The remaining undigested food and water move into the large intestine, where most of the remaining water and electrolytes are absorbed. The waste products are then eliminated from the body.
Breathing and Respiration
Breathing and respiration are two distinct but related processes. Breathing is the physical act of inhaling and exhaling air, while respiration is the chemical process of using that air to release energy within cells. Breathing is a part of respiration, but respiration is a more complex process that happens at a cellular level.
Breathing (External Respiration)
Breathing is the mechanical movement of air into and out of the lungs. It involves two phases:
- Inhalation (Inspiration): The diaphragm and intercostal muscles contract, causing the chest cavity to expand and air to be drawn into the lungs.
- Exhalation (Expiration): The muscles relax, causing the chest cavity to shrink and air to be pushed out of the lungs.
The primary purpose of breathing is to bring oxygen into the body and expel carbon dioxide.
Respiration (Cellular Respiration)
Cellular respiration is a series of chemical reactions that take place inside the cells of organisms to convert biochemical energy from nutrients into ATP (adenosine triphosphate), the main energy currency of the cell. This process uses the oxygen brought in by breathing.
The overall chemical equation for aerobic respiration is: C6H12O6 (glucose) + 6O2 (oxygen) → 6CO2 (carbon dioxide) + 6H2O (water) + ATP (energy)
This process has three main stages:
- Glycolysis: The breakdown of glucose into pyruvate.
- Krebs Cycle: A series of reactions that generate energy-carrying molecules.
- Electron Transport Chain: The final stage where the majority of ATP is produced.
